What is the primary goal of IV thrombolytics in treating acute ischemic stroke?

The primary goal of administering intravenous thrombolytics during the treatment of an acute ischemic stroke is to achieve reperfusion of the affected artery. This is critical because an ischemic stroke occurs due to a blockage, typically by a blood clot, in a cerebral artery that supplies blood to a portion of the brain. By using thrombolytics, the intention is to dissolve the clot, restore blood flow, and minimize the duration of brain tissue being deprived of oxygen and nutrients. This can significantly reduce the extent of brain damage and improve outcomes for the patient if administered within the appropriate time window after the onset of symptoms.

In this context, other options do not align with the primary purpose of thrombolytics. For example, while preventing hemorrhage is a concern in stroke management, thrombolytics themselves do not aim to prevent bleeding; they are associated with a risk of causing it as they dissolve clots. Likewise, the reduction of blood viscosity and increasing blood pressure are not primary goals of thrombolytic therapy. The primary focus remains on achieving rapid reperfusion to restore cerebral blood flow.